Sequence Data & Sequencing Centers
The Kids First Program generates high-quality whole genome sequence data, and whole exome and transcriptome for tumors/affected tissue along with related clinical data, to discover genetic variants that contribute to pediatric conditions. Making this data as accessible as possible to the research community enables researchers to easily combine/compare datasets for cross-dataset analyses. For Germline or Normal samples WGS is supported at 30X coverage and for Tumor or Affected tissue Whole Genome Sequencing is supported at 30X coverage in addition to 100X for whole exome sequencing and 100X for RNAseq.
Four centers were selected to perform the sequencing for the Kids First Program:
HudsonAlpha Institute for Biotechnology
(link is external)
- Shawn Levy, Ph.D, Director of the Genomic Services Lab
- Jinghui Zhang, Ph.D.
- John Easton, Ph.D.
Broad Institute of MIT & Harvard
(link is external)
- Stacey Gabriel, Ph.D., Senior Director, Genomics Platform
- Michael Talkowski, Ph.D.
- Daniel MacArthur, Ph.D.
Baylor College of Medicine Human Genome Sequencing Center
(link is external)
- Richard Gibbs, Ph.D., Director Human Genome Sequencing Center Baylor College of Medicine
McDonnell Genome Institute at Washington University
(link is external)
- Susan Dutcher, Ph.D., Interim Director, The Institute for Genomic Medicine